serB protein (Alkanindiges illinoisensis) - STRING interaction network

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Score

serB

Unannotated protein. (404 aa)

Predicted Functional Partners:

serC

0.972

glyA

0.967

thrH

0.941

hisI

0.917

cysE

0.908

trpB

0.908

GCA_000619845_01617

0.908

ilvA

0.902

pssA

0.900

trpA

0.896

Your Current Organism:

Alkanindiges illinoisensis

NCBI taxonomy Id: 1120977
Other names: A. illinoisensis DSM 15370, Alkanindiges illinoisensis DSM 15370

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCA_000619845_01617	cysE	GCA_000619845_01617	GCA_000619845_00830	Unannotated protein.	Unannotated protein.	0.915
GCA_000619845_01617	glyA	GCA_000619845_01617	GCA_000619845_00355	Unannotated protein.	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.900
GCA_000619845_01617	serB	GCA_000619845_01617	GCA_000619845_02128	Unannotated protein.	Unannotated protein.	0.908
cysE	GCA_000619845_01617	GCA_000619845_00830	GCA_000619845_01617	Unannotated protein.	Unannotated protein.	0.915
cysE	glyA	GCA_000619845_00830	GCA_000619845_00355	Unannotated protein.	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.900
cysE	serB	GCA_000619845_00830	GCA_000619845_02128	Unannotated protein.	Unannotated protein.	0.908
glyA	GCA_000619845_01617	GCA_000619845_00355	GCA_000619845_01617	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein.	0.900
glyA	cysE	GCA_000619845_00355	GCA_000619845_00830	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein.	0.900
glyA	ilvA	GCA_000619845_00355	GCA_000619845_00708	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.920
glyA	serB	GCA_000619845_00355	GCA_000619845_02128	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein.	0.967
glyA	serC	GCA_000619845_00355	GCA_000619845_01113	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.547
glyA	thrH	GCA_000619845_00355	GCA_000619845_01456	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein.	0.950
glyA	trpA	GCA_000619845_00355	GCA_000619845_01561	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.925
glyA	trpB	GCA_000619845_00355	GCA_000619845_01569	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.920
hisI	ilvA	GCA_000619845_02426	GCA_000619845_00708	Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.	Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.401
hisI	serB	GCA_000619845_02426	GCA_000619845_02128	Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.	Unannotated protein.	0.917
hisI	thrH	GCA_000619845_02426	GCA_000619845_01456	Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.	Unannotated protein.	0.913
hisI	trpA	GCA_000619845_02426	GCA_000619845_01561	Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.	Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.665
hisI	trpB	GCA_000619845_02426	GCA_000619845_01569	Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.	Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.547
ilvA	glyA	GCA_000619845_00708	GCA_000619845_00355	Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.920