node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SES78888.1 | SET05704.1 | SAMN03080614_10083 | SAMN03080614_10399 | Site-2 protease. Metallo peptidase. MEROPS family M50B. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.668 |
SES78888.1 | ffh | SAMN03080614_10083 | SAMN03080614_103915 | Site-2 protease. Metallo peptidase. MEROPS family M50B. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.443 |
SES78888.1 | topA | SAMN03080614_10083 | SAMN03080614_100854 | Site-2 protease. Metallo peptidase. MEROPS family M50B. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.730 |
SET04066.1 | SET05704.1 | SAMN03080614_10366 | SAMN03080614_10399 | Bifunctional non-homologous end joining protein LigD. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.904 |
SET05634.1 | SET05685.1 | SAMN03080614_10395 | SAMN03080614_10398 | Putative endonuclease; Belongs to the UPF0102 family. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.655 |
SET05634.1 | SET05704.1 | SAMN03080614_10395 | SAMN03080614_10399 | Putative endonuclease; Belongs to the UPF0102 family. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.672 |
SET05634.1 | ffh | SAMN03080614_10395 | SAMN03080614_103915 | Putative endonuclease; Belongs to the UPF0102 family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.404 |
SET05634.1 | rnhB | SAMN03080614_10395 | SAMN03080614_10397 | Putative endonuclease; Belongs to the UPF0102 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.820 |
SET05634.1 | rplS | SAMN03080614_10395 | SAMN03080614_103910 | Putative endonuclease; Belongs to the UPF0102 family. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.620 |
SET05634.1 | topA | SAMN03080614_10395 | SAMN03080614_100854 | Putative endonuclease; Belongs to the UPF0102 family. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.402 |
SET05685.1 | SET05634.1 | SAMN03080614_10398 | SAMN03080614_10395 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Putative endonuclease; Belongs to the UPF0102 family. | 0.655 |
SET05685.1 | SET05704.1 | SAMN03080614_10398 | SAMN03080614_10399 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.816 |
SET05685.1 | ffh | SAMN03080614_10398 | SAMN03080614_103915 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.449 |
SET05685.1 | rnhB | SAMN03080614_10398 | SAMN03080614_10397 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.808 |
SET05685.1 | rplS | SAMN03080614_10398 | SAMN03080614_103910 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.964 |
SET05685.1 | topA | SAMN03080614_10398 | SAMN03080614_100854 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.472 |
SET05704.1 | SES78888.1 | SAMN03080614_10399 | SAMN03080614_10083 | Signal peptidase I; Belongs to the peptidase S26 family. | Site-2 protease. Metallo peptidase. MEROPS family M50B. | 0.668 |
SET05704.1 | SET04066.1 | SAMN03080614_10399 | SAMN03080614_10366 | Signal peptidase I; Belongs to the peptidase S26 family. | Bifunctional non-homologous end joining protein LigD. | 0.904 |
SET05704.1 | SET05634.1 | SAMN03080614_10399 | SAMN03080614_10395 | Signal peptidase I; Belongs to the peptidase S26 family. | Putative endonuclease; Belongs to the UPF0102 family. | 0.672 |
SET05704.1 | SET05685.1 | SAMN03080614_10399 | SAMN03080614_10398 | Signal peptidase I; Belongs to the peptidase S26 family. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.816 |