SHH61959.1 protein (Anaerosphaera aminiphila)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SHH61959.1

Listeria/Bacterioides repeat-containing protein. (688 aa)

Predicted Functional Partners:

SHH43029.1

0.808

SHH28124.1

0.777

SHH11084.1

0.776

SHH54954.1

0.776

SHH68404.1

0.776

SHH31387.1

0.775

SHH20241.1

0.773

SHH20515.1

0.773

SHH55742.1

0.754

SHH44962.1

0.746

Your Current Organism:

Anaerosphaera aminiphila

NCBI taxonomy Id: 1120995
Other names: A. aminiphila DSM 21120, Anaerosphaera aminiphila DSM 21120, Anaerosphaera aminiphila WN036, Peptostreptococcaceae bacterium WN036

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHH11084.1	SHH20241.1	SAMN02745245_00575	SAMN02745245_00785	Copper amine oxidase N-terminal domain-containing protein.	Polysaccharide pyruvyl transferase CsaB.	0.766
SHH11084.1	SHH20515.1	SAMN02745245_00575	SAMN02745245_00793	Copper amine oxidase N-terminal domain-containing protein.	Copper amine oxidase N-terminal domain-containing protein.	0.775
SHH11084.1	SHH43029.1	SAMN02745245_00575	SAMN02745245_01303	Copper amine oxidase N-terminal domain-containing protein.	S-layer homology domain-containing protein.	0.780
SHH11084.1	SHH54954.1	SAMN02745245_00575	SAMN02745245_01592	Copper amine oxidase N-terminal domain-containing protein.	Copper amine oxidase N-terminal domain-containing protein.	0.775
SHH11084.1	SHH55742.1	SAMN02745245_00575	SAMN02745245_01593	Copper amine oxidase N-terminal domain-containing protein.	S-layer homology domain-containing protein.	0.774
SHH11084.1	SHH61959.1	SAMN02745245_00575	SAMN02745245_01763	Copper amine oxidase N-terminal domain-containing protein.	Listeria/Bacterioides repeat-containing protein.	0.776
SHH11084.1	SHH68404.1	SAMN02745245_00575	SAMN02745245_01929	Copper amine oxidase N-terminal domain-containing protein.	Copper amine oxidase N-terminal domain-containing protein.	0.775
SHH20241.1	SHH11084.1	SAMN02745245_00785	SAMN02745245_00575	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.766
SHH20241.1	SHH20515.1	SAMN02745245_00785	SAMN02745245_00793	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.769
SHH20241.1	SHH28124.1	SAMN02745245_00785	SAMN02745245_00985	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.771
SHH20241.1	SHH31387.1	SAMN02745245_00785	SAMN02745245_01051	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.769
SHH20241.1	SHH43029.1	SAMN02745245_00785	SAMN02745245_01303	Polysaccharide pyruvyl transferase CsaB.	S-layer homology domain-containing protein.	0.765
SHH20241.1	SHH44962.1	SAMN02745245_00785	SAMN02745245_01362	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.755
SHH20241.1	SHH54954.1	SAMN02745245_00785	SAMN02745245_01592	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.765
SHH20241.1	SHH55742.1	SAMN02745245_00785	SAMN02745245_01593	Polysaccharide pyruvyl transferase CsaB.	S-layer homology domain-containing protein.	0.735
SHH20241.1	SHH61959.1	SAMN02745245_00785	SAMN02745245_01763	Polysaccharide pyruvyl transferase CsaB.	Listeria/Bacterioides repeat-containing protein.	0.773
SHH20241.1	SHH68404.1	SAMN02745245_00785	SAMN02745245_01929	Polysaccharide pyruvyl transferase CsaB.	Copper amine oxidase N-terminal domain-containing protein.	0.768
SHH20515.1	SHH11084.1	SAMN02745245_00793	SAMN02745245_00575	Copper amine oxidase N-terminal domain-containing protein.	Copper amine oxidase N-terminal domain-containing protein.	0.775
SHH20515.1	SHH20241.1	SAMN02745245_00793	SAMN02745245_00785	Copper amine oxidase N-terminal domain-containing protein.	Polysaccharide pyruvyl transferase CsaB.	0.769
SHH20515.1	SHH43029.1	SAMN02745245_00793	SAMN02745245_01303	Copper amine oxidase N-terminal domain-containing protein.	S-layer homology domain-containing protein.	0.772

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Network Stats

number of nodes:

11

number of edges:

28

average node degree:

5.09

avg. local clustering coefficient:

0.858

expected number of edges:

18

PPI enrichment p-value:

0.0174

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006810

Transport

10 of 548

0.88

0.89

8.16e-06

GO:0009306

Protein secretion

3 of 46

1.44

0.64

0.0482

GO:0033036

Macromolecule localization

4 of 143

1.07

0.54

0.0482

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

6 of 20

2.1

3.89

3.13e-09

GO:0042626

ATPase-coupled transmembrane transporter activity

7 of 34

1.94

3.8

6.57e-10

GO:0005524

ATP binding

7 of 380

0.89

0.74

0.00091

GO:0043167

Ion binding

8 of 1093

0.49

0.32

0.0334

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

9 of 921

0.61

0.48

0.0015

GO:0016020

Membrane

11 of 1396

0.52

0.44

0.00030

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7435

RTX calcium-binding nonapeptide repeat (4 copies), and ABC transporter transmembrane region

7 of 10

2.47

5.97

7.25e-13

CL:7436

ABC transporter transmembrane region, and RTX calcium-binding nonapeptide repeat (4 copies)

5 of 5

2.62

4.44

3.36e-09

CL:7445

RTX calcium-binding nonapeptide repeat (4 copies), and ABC transporter transmembrane region

2 of 5

2.23

0.9

0.0220

CL:5757

ABC transporter transmembrane region, and Cation transport ATPase (P-type)

2 of 6

2.15

0.87

0.0245

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

7 of 105

1.45

2.11

1.66e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1222449

Mtb iron assimilation by chelation

2 of 4

2.32

1.42

0.0022

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030256

Type I protein secretion system complex

3 of 9

2.15

1.64

0.00070

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0067

ATP-binding

7 of 273

1.03

0.98

0.00016

KW-0472

Membrane

9 of 924

0.61

0.48

0.0015

KW-1133

Transmembrane helix

8 of 808

0.62

0.46

0.0050

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00664

ABC transporter transmembrane region

5 of 7

2.48

4.04

1.41e-08

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

5 of 71

1.47

1.61

5.60e-05

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