node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHM07542.1 | SHM07563.1 | SAMN02746066_00648 | SAMN02746066_00649 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Predicted kinase. | 0.698 |
SHM07542.1 | SHM07585.1 | SAMN02746066_00648 | SAMN02746066_00650 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Ribosomal protection tetracycline resistance protein. | 0.642 |
SHM07542.1 | SHM52677.1 | SAMN02746066_00648 | SAMN02746066_02297 | DNA-binding transcriptional regulator, XRE-family HTH domain. | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes. | 0.583 |
SHM07542.1 | SHM55627.1 | SAMN02746066_00648 | SAMN02746066_02371 | DNA-binding transcriptional regulator, XRE-family HTH domain. | PTS system D-fructose-specific IIA component (F1P-forming), Frc family /PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-forming), Frc family. | 0.504 |
SHM07542.1 | SHN02431.1 | SAMN02746066_00648 | SAMN02746066_04443 | DNA-binding transcriptional regulator, XRE-family HTH domain. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.696 |
SHM07542.1 | cinA | SAMN02746066_00648 | SAMN02746066_00130 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | 0.606 |
SHM07542.1 | nadE | SAMN02746066_00648 | SAMN02746066_03211 | DNA-binding transcriptional regulator, XRE-family HTH domain. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.549 |
SHM07542.1 | pfkA | SAMN02746066_00648 | SAMN02746066_01334 | DNA-binding transcriptional regulator, XRE-family HTH domain. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.520 |
SHM07542.1 | pfkA-2 | SAMN02746066_00648 | SAMN02746066_01999 | DNA-binding transcriptional regulator, XRE-family HTH domain. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.520 |
SHM07542.1 | pfp | SAMN02746066_00648 | SAMN02746066_01358 | DNA-binding transcriptional regulator, XRE-family HTH domain. | 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.520 |
SHM07563.1 | SHM07542.1 | SAMN02746066_00649 | SAMN02746066_00648 | Predicted kinase. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.698 |
SHM07563.1 | SHM07585.1 | SAMN02746066_00649 | SAMN02746066_00650 | Predicted kinase. | Ribosomal protection tetracycline resistance protein. | 0.705 |
SHM07585.1 | SHM07542.1 | SAMN02746066_00650 | SAMN02746066_00648 | Ribosomal protection tetracycline resistance protein. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.642 |
SHM07585.1 | SHM07563.1 | SAMN02746066_00650 | SAMN02746066_00649 | Ribosomal protection tetracycline resistance protein. | Predicted kinase. | 0.705 |
SHM52677.1 | SHM07542.1 | SAMN02746066_02297 | SAMN02746066_00648 | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.583 |
SHM52677.1 | cinA | SAMN02746066_02297 | SAMN02746066_00130 | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes. | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | 0.960 |
SHM52677.1 | nadE | SAMN02746066_02297 | SAMN02746066_03211 | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.966 |
SHM55627.1 | SHM07542.1 | SAMN02746066_02371 | SAMN02746066_00648 | PTS system D-fructose-specific IIA component (F1P-forming), Frc family /PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-forming), Frc family. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.504 |
SHM55627.1 | nadE | SAMN02746066_02371 | SAMN02746066_03211 | PTS system D-fructose-specific IIA component (F1P-forming), Frc family /PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-forming), Frc family. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.418 |
SHM55627.1 | pfkA | SAMN02746066_02371 | SAMN02746066_01334 | PTS system D-fructose-specific IIA component (F1P-forming), Frc family /PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-forming), Frc family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.675 |