KFL37722.1 protein (Arenimonas donghaensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KFL37722.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (253 aa)

Predicted Functional Partners:

KFL37721.1

0.752

KFL37718.1

0.609

KFL37719.1

0.609

KFL37720.1

0.609

KFL37717.1

0.421

Your Current Organism:

Arenimonas donghaensis

NCBI taxonomy Id: 1121014
Other names: A. donghaensis DSM 18148 = HO3-R19, Arenimonas donghaensis DSM 18148, Arenimonas donghaensis DSM 18148 = HO3-R19, Arenimonas donghaensis HO3-R19

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KFL37717.1	KFL37718.1	N788_00680	N788_00685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KFL37717.1	KFL37719.1	N788_00680	N788_00690	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KFL37717.1	KFL37720.1	N788_00680	N788_00695	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KFL37717.1	KFL37721.1	N788_00680	N788_00700	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.431
KFL37717.1	KFL37722.1	N788_00680	N788_00705	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.421
KFL37718.1	KFL37717.1	N788_00685	N788_00680	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KFL37718.1	KFL37719.1	N788_00685	N788_00690	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.992
KFL37718.1	KFL37720.1	N788_00685	N788_00695	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.957
KFL37718.1	KFL37721.1	N788_00685	N788_00700	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.918
KFL37718.1	KFL37722.1	N788_00685	N788_00705	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.609
KFL37719.1	KFL37717.1	N788_00690	N788_00680	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KFL37719.1	KFL37718.1	N788_00690	N788_00685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.992
KFL37719.1	KFL37720.1	N788_00690	N788_00695	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.985
KFL37719.1	KFL37721.1	N788_00690	N788_00700	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.926
KFL37719.1	KFL37722.1	N788_00690	N788_00705	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.609
KFL37720.1	KFL37717.1	N788_00695	N788_00680	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.520
KFL37720.1	KFL37718.1	N788_00695	N788_00685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.957
KFL37720.1	KFL37719.1	N788_00695	N788_00690	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.985
KFL37720.1	KFL37721.1	N788_00695	N788_00700	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.914
KFL37720.1	KFL37722.1	N788_00695	N788_00705	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.609

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.904

expected number of edges:

26

PPI enrichment p-value:

0.86

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006310

DNA recombination

8 of 68

2.02

4.65

4.87e-12

GO:0000724

Double-strand break repair via homologous recombination

6 of 37

2.15

4.06

1.85e-09

GO:0006302

Double-strand break repair

7 of 64

1.98

3.97

4.14e-10

GO:0000730

DNA recombinase assembly

4 of 5

2.85

3.91

5.80e-08

GO:0006312

Mitotic recombination

4 of 12

2.47

3.31

4.47e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140664

ATP-dependent DNA damage sensor activity

4 of 14

2.4

2.89

2.75e-06

GO:0008094

ATP-dependent activity, acting on DNA

5 of 68

1.81

2.42

2.87e-06

GO:0140097

Catalytic activity, acting on DNA

6 of 121

1.64

2.19

2.75e-06

GO:0000150

DNA strand exchange activity

2 of 3

2.77

1.59

0.0013

GO:0003697

Single-stranded DNA binding

3 of 31

1.93

1.56

0.00075

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033061

DNA recombinase mediator complex

3 of 4

2.82

2.49

2.75e-05

GO:0005694

Chromosome

4 of 298

1.07

0.61

0.0265

GO:0005634

Nucleus

10 of 1915

0.66

0.56

0.00030

GO:0043231

Intracellular membrane-bounded organelle

11 of 3750

0.41

0.32

0.0071

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3707

Homologous recombination, and DNA secondary structure binding

10 of 29

2.48

9.3

4.91e-21

CL:3705

Mismatch repair, and Homologous recombination

11 of 65

2.17

7.84

4.91e-21

CL:3709

Mixed, incl. HDR through Single Strand Annealing (SSA), and Sensing of DNA Double Strand Breaks

6 of 23

2.36

5.13

2.61e-11

CL:3712

HDR through Single Strand Annealing (SSA), and DNA replication factor A complex

4 of 8

2.64

3.84

5.62e-08

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03440

Homologous recombination

8 of 48

2.17

5.87

1.74e-14

map03430

Mismatch repair

3 of 46

1.76

1.37

0.0014

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5685942

HDR through Homologous Recombination (HRR)

8 of 23

2.49

7.5

2.06e-16

MAP-5693567

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

9 of 36

2.34

7.45

2.15e-17

MAP-5693538

Homology Directed Repair

9 of 37

2.33

7.41

2.15e-17

MAP-5693579

Homologous DNA Pairing and Strand Exchange

7 of 13

2.68

7.37

2.95e-15

MAP-5693616

Presynaptic phase of homologous DNA pairing and strand exchange

6 of 12

2.64

6.15

9.79e-13

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033061

DNA recombinase mediator complex

3 of 4

2.82

2.44

3.40e-05

GOCC:0033063

Rad51B-Rad51C-Rad51D-XRCC2 complex

2 of 2

2.95

1.39

0.0031

GOCC:0005634

Nucleus

7 of 1123

0.74

0.5

0.0111

GOCC:0043229

Intracellular organelle

11 of 3327

0.46

0.37

0.0031

GOCC:0043231

Intracellular membrane-bounded organelle

9 of 2475

0.51

0.34

0.0228

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0539

Nucleus

4 of 243

1.16

0.64

0.0275

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR027417

P-loop containing nucleoside triphosphate hydrolase

7 of 335

1.27

1.36

4.81e-05

IPR020588

DNA recombination and repair protein RecA-like, ATP-binding domain

2 of 2

2.95

1.13

0.0091

IPR013632

DNA recombination and repair protein Rad51-like, C-terminal

2 of 2

2.95

1.13

0.0091

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Textmining

Fusion

Experiments

Cooccurrence

Databases

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About