SHG98203.1 protein (Asaccharospora irregularis)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

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Score

SHG98203.1

Putative membrane protein. (648 aa)

Predicted Functional Partners:

SHG98235.1

0.994

SHG98260.1

0.732

SHH14311.1

0.542

SHH48643.1

0.518

SHG94474.1

0.509

SHG61471.1

0.503

SHG67576.1

0.451

SHG82650.1

0.434

SHG98169.1

0.424

Your Current Organism:

Asaccharospora irregularis

NCBI taxonomy Id: 1121321
Other names: A. irregularis DSM 2635, Asaccharospora irregularis DSM 2635, Clostridium irregulare DSM 2635

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHG61471.1	SHG98203.1	SAMN04488530_10444	SAMN04488530_11341	Putative ABC transport system permease protein.	Putative membrane protein.	0.503
SHG67576.1	SHG98203.1	SAMN04488530_10556	SAMN04488530_11341	Conserved hypothetical integral membrane protein TIGR02206.	Putative membrane protein.	0.451
SHG67576.1	SHH48643.1	SAMN04488530_10556	SAMN04488530_1572	Conserved hypothetical integral membrane protein TIGR02206.	Putative ABC transport system permease protein.	0.428
SHG82650.1	SHG98203.1	SAMN04488530_10878	SAMN04488530_11341	Stage V sporulation protein B.	Putative membrane protein.	0.434
SHG94474.1	SHG98203.1	SAMN04488530_11226	SAMN04488530_11341	Putative ABC transport system permease protein.	Putative membrane protein.	0.509
SHG98169.1	SHG98203.1	SAMN04488530_11340	SAMN04488530_11341	Hypothetical protein.	Putative membrane protein.	0.424
SHG98203.1	SHG61471.1	SAMN04488530_11341	SAMN04488530_10444	Putative membrane protein.	Putative ABC transport system permease protein.	0.503
SHG98203.1	SHG67576.1	SAMN04488530_11341	SAMN04488530_10556	Putative membrane protein.	Conserved hypothetical integral membrane protein TIGR02206.	0.451
SHG98203.1	SHG82650.1	SAMN04488530_11341	SAMN04488530_10878	Putative membrane protein.	Stage V sporulation protein B.	0.434
SHG98203.1	SHG94474.1	SAMN04488530_11341	SAMN04488530_11226	Putative membrane protein.	Putative ABC transport system permease protein.	0.509
SHG98203.1	SHG98169.1	SAMN04488530_11341	SAMN04488530_11340	Putative membrane protein.	Hypothetical protein.	0.424
SHG98203.1	SHG98235.1	SAMN04488530_11341	SAMN04488530_11342	Putative membrane protein.	Hypothetical protein.	0.994
SHG98203.1	SHG98260.1	SAMN04488530_11341	SAMN04488530_11343	Putative membrane protein.	Regulatory protein, tetR family.	0.732
SHG98203.1	SHH14311.1	SAMN04488530_11341	SAMN04488530_1225	Putative membrane protein.	DNA-binding transcriptional regulator, AcrR family.	0.542
SHG98203.1	SHH48643.1	SAMN04488530_11341	SAMN04488530_1572	Putative membrane protein.	Putative ABC transport system permease protein.	0.518
SHG98235.1	SHG98203.1	SAMN04488530_11342	SAMN04488530_11341	Hypothetical protein.	Putative membrane protein.	0.994
SHG98235.1	SHG98260.1	SAMN04488530_11342	SAMN04488530_11343	Hypothetical protein.	Regulatory protein, tetR family.	0.595
SHG98235.1	SHH14311.1	SAMN04488530_11342	SAMN04488530_1225	Hypothetical protein.	DNA-binding transcriptional regulator, AcrR family.	0.499
SHG98260.1	SHG98203.1	SAMN04488530_11343	SAMN04488530_11341	Regulatory protein, tetR family.	Putative membrane protein.	0.732
SHG98260.1	SHG98235.1	SAMN04488530_11343	SAMN04488530_11342	Regulatory protein, tetR family.	Hypothetical protein.	0.595

page 1 of 2

Network Stats

number of nodes:

7

number of edges:

12

average node degree:

3.43

avg. local clustering coefficient:

0.795

expected number of edges:

6

PPI enrichment p-value:

0.0245

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

11 of 17

2.59

11.22

6.40e-25

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 5

2.38

1.38

0.0028

GO:0005524

ATP binding

5 of 481

0.8

0.49

0.0253

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

11 of 17

2.59

11.48

1.35e-25

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

6 of 10

2.56

6.26

3.31e-13

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

5 of 7

2.63

5.43

3.04e-11

GO:0031676

Plasma membrane-derived thylakoid membrane

11 of 123

1.73

4.67

8.61e-18

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1123

Proton channel activity

11 of 18

2.57

10.94

1.75e-24

CL:1125

ATP synthesis

10 of 13

2.67

10.51

1.91e-22

CL:1126

ATP synthesis

6 of 7

2.71

6.17

1.31e-12

CL:1139

ATP synthesis

4 of 6

2.6

3.61

1.46e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00195

Photosynthesis

11 of 80

1.92

5.98

2.32e-19

map00190

Oxidative phosphorylation

11 of 88

1.88

5.72

3.09e-19

map01100

Metabolic pathways

11 of 2083

0.5

0.43

0.00014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

11 of 18

2.57

11.19

3.96e-25

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

6 of 10

2.56

5.87

2.41e-12

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

5 of 8

2.58

4.92

2.85e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0066

ATP synthesis

11 of 16

2.62

11.63

1.10e-25

KW-0375

Hydrogen ion transport

11 of 19

2.54

11.16

2.29e-25

KW-0139

CF(1)

6 of 9

2.6

6.16

7.38e-13

KW-0138

CF(0)

5 of 7

2.63

5.17

1.10e-10

KW-0793

Thylakoid

11 of 108

1.79

5.07

2.21e-18

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00430

ATP synthase B/B CF(0)

3 of 3

2.78

2.32

5.65e-05

PF00231

ATP synthase

2 of 2

2.78

1.22

0.0062

PF02874

ATP synthase alpha/beta family, beta-barrel domain

2 of 4

2.48

1.08

0.0104

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