STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHH00871.1Tyrosine lyase ThiH. (367 aa)    
Predicted Functional Partners:
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 0.999
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
 0.966
SHH00958.1
Sulfur carrier protein.
 
 
  0.932
SHH00843.1
Thiamine-phosphate pyrophosphorylase.
  
  
 0.921
SHH00929.1
Sulfur carrier protein ThiS adenylyltransferase.
 
    0.883
SHG56772.1
2-iminoacetate synthase.
  
  
 
0.871
SHG60181.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
    0.742
SHG78137.1
GAF domain-containing protein.
   
    0.739
SHG87347.1
Flagellar basal-body rod protein FlgB.
   
    0.739
SHG56746.1
[FeFe] hydrogenase H-cluster maturation GTPase HydF.
   
 0.733
Your Current Organism:
Asaccharospora irregularis
NCBI taxonomy Id: 1121321
Other names: A. irregularis DSM 2635, Asaccharospora irregularis DSM 2635, Clostridium irregulare DSM 2635
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