STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queE7-carboxy-7-deazaguanine synthase QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (220 aa)    
Predicted Functional Partners:
queD
6-carboxy-5,6,7,8-tetrahydropterin synthase QueD.
 
 
 0.997
queC
7-cyano-7-deazaguanine synthase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
 
 0.996
queD-2
6-carboxy-5,6,7,8-tetrahydropterin synthase QueD.
 
 
 0.981
queC-2
7-cyano-7-deazaguanine synthase QueC.
 
 
 0.969
KDR95337.1
2-hydroxyglutaryl-CoA dehydratase, D-component.
 
    0.876
fldI
R-phenyllactate dehydratase activator.
 
     0.812
nrdD
Anaerobic ribonucleoside-triphosphate reductase NrdD.
  
 
 0.801
KDR94345.1
Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase.
  
 
 0.801
folE
GTP cyclohydrolase 1.
  
  
 0.707
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.630
Your Current Organism:
Peptoclostridium litorale
NCBI taxonomy Id: 1121324
Other names: Clostridium litorale (strain W6), Clostridium litorale DSM 5388, P. litorale DSM 5388, Peptoclostridium litorale DSM 5388, bacterium W6
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