STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mucDPutative periplasmic serine endoprotease DegP. (350 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.880
KDR95409.1
Hypothetical protein.
       0.747
KDR95407.1
Short-chain dehydrogenase/reductase SDR.
  
 0.738
barA
Signal transduction histidine-protein kinase BarA.
  
  
 0.726
KDR95613.1
OmpA/MotB domain-containing protein.
   
 
 0.663
KDR95527.1
Diguanylate cyclase/phosphodiesterase.
  
  
 0.662
leuA
2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
 0.636
alaS
alanine--tRNA ligase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
 0.635
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.633
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.620
Your Current Organism:
Peptoclostridium litorale
NCBI taxonomy Id: 1121324
Other names: Clostridium litorale (strain W6), Clostridium litorale DSM 5388, P. litorale DSM 5388, Peptoclostridium litorale DSM 5388, bacterium W6
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