KDR94184.1 protein (Peptoclostridium litorale)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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KDR94184.1

Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (620 aa)

Predicted Functional Partners:

KDR94183.1

0.984

KDR95417.1

0.670

KDR95423.1

0.518

fur

0.472

KDR94182.1

0.440

KDR94181.1

0.423

leuS

0.416

zupT

0.405

Your Current Organism:

Peptoclostridium litorale

NCBI taxonomy Id: 1121324
Other names: Clostridium litorale (strain W6), Clostridium litorale DSM 5388, P. litorale DSM 5388, Peptoclostridium litorale DSM 5388, bacterium W6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KDR94181.1	KDR94182.1	CLIT_23c04540	CLIT_23c04550	Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.	Hypothetical protein; Belongs to the UPF0473 family.	0.954
KDR94181.1	KDR94183.1	CLIT_23c04540	CLIT_23c04560	Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.	Hypothetical protein.	0.424
KDR94181.1	KDR94184.1	CLIT_23c04540	CLIT_23c04570	Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	0.423
KDR94182.1	KDR94181.1	CLIT_23c04550	CLIT_23c04540	Hypothetical protein; Belongs to the UPF0473 family.	Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.	0.954
KDR94182.1	KDR94183.1	CLIT_23c04550	CLIT_23c04560	Hypothetical protein; Belongs to the UPF0473 family.	Hypothetical protein.	0.455
KDR94182.1	KDR94184.1	CLIT_23c04550	CLIT_23c04570	Hypothetical protein; Belongs to the UPF0473 family.	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	0.440
KDR94182.1	fur	CLIT_23c04550	CLIT_23c04580	Hypothetical protein; Belongs to the UPF0473 family.	Ferric uptake regulation protein Fur; Belongs to the Fur family.	0.564
KDR94183.1	KDR94181.1	CLIT_23c04560	CLIT_23c04540	Hypothetical protein.	Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.	0.424
KDR94183.1	KDR94182.1	CLIT_23c04560	CLIT_23c04550	Hypothetical protein.	Hypothetical protein; Belongs to the UPF0473 family.	0.455
KDR94183.1	KDR94184.1	CLIT_23c04560	CLIT_23c04570	Hypothetical protein.	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	0.984
KDR94183.1	KDR95423.1	CLIT_23c04560	CLIT_10c01500	Hypothetical protein.	Hypothetical protein.	0.761
KDR94183.1	fur	CLIT_23c04560	CLIT_23c04580	Hypothetical protein.	Ferric uptake regulation protein Fur; Belongs to the Fur family.	0.490
KDR94184.1	KDR94181.1	CLIT_23c04570	CLIT_23c04540	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.	0.423
KDR94184.1	KDR94182.1	CLIT_23c04570	CLIT_23c04550	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Hypothetical protein; Belongs to the UPF0473 family.	0.440
KDR94184.1	KDR94183.1	CLIT_23c04570	CLIT_23c04560	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Hypothetical protein.	0.984
KDR94184.1	KDR95417.1	CLIT_23c04570	CLIT_10c01440	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Hypothetical protein.	0.670
KDR94184.1	KDR95423.1	CLIT_23c04570	CLIT_10c01500	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Hypothetical protein.	0.518
KDR94184.1	fur	CLIT_23c04570	CLIT_23c04580	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Ferric uptake regulation protein Fur; Belongs to the Fur family.	0.472
KDR94184.1	leuS	CLIT_23c04570	CLIT_23c03520	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	leucine--tRNA ligase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.416
KDR94184.1	zupT	CLIT_23c04570	CLIT_5c00520	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	Zinc transporter ZupT; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.	0.405

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Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 110

1.55

3.37

2.00e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 56

1.84

5.25

1.16e-17

GO:0019843

rRNA binding

10 of 45

1.9

5.25

3.40e-16

GO:0003723

RNA binding

11 of 123

1.5

3.19

9.30e-15

GO:0000049

tRNA binding

3 of 24

1.65

1.13

0.0042

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 60

1.81

5.17

3.58e-18

GO:0015935

Small ribosomal subunit

3 of 8

2.12

2.17

5.02e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34412707

(2021) The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum.

5 of 11

2.21

3.04

7.59e-07

PMID:37589280

(2023) L. rhamnosus CNCM I-3690 survival, adaptation, and small bowel microbiome impact in human.

6 of 23

1.97

2.98

2.51e-07

PMID:22043294

(2011) Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.

4 of 9

2.2

2.22

4.62e-05

PMID:23342046

(2013) The genome sequences of Cellulomonas fimi and Cellvibrio gilvus reveal the cellulolytic strategies of two facultative anaerobes, transfer of Cellvibrio gilvus to the genus Cellulomonas, and proposal of Cellulomonas gilvus sp. nov.

5 of 32

1.74

1.92

4.62e-05

PMID:18851752

(2008) A simple, fast, and accurate method of phylogenomic inference.

5 of 34

1.72

1.9

4.62e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:164

Small ribosomal subunit, and rRNA-binding

8 of 11

2.41

7.01

1.15e-15

CL:124

Structural constituent of ribosome

11 of 57

1.83

5.18

1.73e-17

CL:224

Mixed, incl. Translation elongation factor EF1B/ribosomal protein S6, and Ribosomal protein S5 domain 2-type fold, subgroup

3 of 6

2.25

2.16

6.91e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cbut03010

Ribosome

11 of 56

1.84

5.4

1.69e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 44

1.86

4.56

1.10e-13

GOCC:0015935

Small ribosomal subunit

4 of 8

2.25

3.07

7.38e-07

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 7

2.18

2.17

5.82e-05

GOCC:0043229

Intracellular organelle

11 of 326

1.08

1.48

2.26e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

10 of 43

1.92

5.49

6.60e-17

KW-0689

Ribosomal protein

11 of 59

1.82

5.18

5.70e-18

KW-0820

tRNA-binding

2 of 15

1.67

0.71

0.0401

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