STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDR95914.1Integrase family protein. (181 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase NifJ.
    
  0.815
KDR95915.1
Hypothetical protein.
       0.588
KDR94752.1
Phosphoribosyl transferase domain-containing protein.
   
    0.523
tyrA
Prephenate dehydrogenase TyrA.
  
    0.504
KDR95913.1
Putative endonuclease.
     
 0.498
whiA
Putative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation.
   
    0.491
KDR95916.1
Hypothetical protein.
       0.487
proC
Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.443
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.434
topB-2
DNA topoisomerase 3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.407
Your Current Organism:
Peptoclostridium litorale
NCBI taxonomy Id: 1121324
Other names: Clostridium litorale (strain W6), Clostridium litorale DSM 5388, P. litorale DSM 5388, Peptoclostridium litorale DSM 5388, bacterium W6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.