STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL49828.1Signal peptidase I; Belongs to the peptidase S26 family. (178 aa)    
Predicted Functional Partners:
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.647
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.640
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.609
SDL53146.1
Regulator of sigma E protease.
 
  
 0.600
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
 
  
 0.577
SDL49921.1
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
   
 
 0.537
SDL49861.1
DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family.
       0.529
SDM10118.1
Stage V sporulation protein D (sporulation-specific penicillin-binding protein).
 
  
 0.521
SDM25900.1
RNA polymerase, sigma 54 subunit, RpoN/SigL.
  
  
 0.521
SDL49800.1
UDP-N-acetylglucosamine 4,6-dehydratase (inverting).
  
    0.519
Your Current Organism:
Romboutsia lituseburensis
NCBI taxonomy Id: 1121325
Other names: Clostridium lituseburense DSM 797, R. lituseburensis DSM 797, Romboutsia lituseburensis ATCC 25759, Romboutsia lituseburensis DSM 797
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.