STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHJ77109.18-oxo-dGTP diphosphatase. (63 aa)    
Predicted Functional Partners:
SHJ69118.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.840
SHJ77139.1
8-oxo-dGTP diphosphatase.
       0.773
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.738
SHJ95008.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.717
SHJ86354.1
Amidohydrolase, PncC family; Belongs to the CinA family.
    
  0.713
SHJ77076.1
Protein of unknown function.
       0.668
SHJ91331.1
Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.668
SHJ77171.1
NADPH-dependent FMN reductase.
       0.658
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.465
SHK10591.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
  
 
  0.436
Your Current Organism:
Hathewaya proteolytica
NCBI taxonomy Id: 1121331
Other names: Clostridium proteolyticum DSM 3090, H. proteolytica DSM 3090, Hathewaya proteolytica DSM 3090
Server load: low (16%) [HD]