STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK00356.1cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases. (224 aa)    
Predicted Functional Partners:
SHJ69118.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.906
SHK00384.1
4Fe-4S binding domain-containing protein.
 
     0.844
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.789
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.777
SHK10591.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
   
 0.758
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.734
SHK49196.1
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases.
  
     0.733
SHJ95008.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.727
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.715
SHK20450.1
Diguanylate cyclase (GGDEF) domain-containing protein.
  
 0.627
Your Current Organism:
Hathewaya proteolytica
NCBI taxonomy Id: 1121331
Other names: Clostridium proteolyticum DSM 3090, H. proteolytica DSM 3090, Hathewaya proteolytica DSM 3090
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.