STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK10416.1CRISPR-associated endoribonuclease Cas6. (244 aa)    
Predicted Functional Partners:
SHK10258.1
CRISPR-associated endonuclease/helicase Cas3.
 
   
 0.967
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.966
SHK10290.1
CRISPR-associated protein Cas5t.
 
   
 0.964
SHK10240.1
CRISPR-associated exonuclease Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.963
SHK10325.1
CRISPR-associated protein Cst2.
 
   
 0.962
cas1
CRISP-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.957
SHK10350.1
CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP.
 
   
 0.950
SHK10383.1
CRISPR-associated protein Cst1.
 
   
 0.950
SHK10445.1
Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains.
 
     0.739
Your Current Organism:
Hathewaya proteolytica
NCBI taxonomy Id: 1121331
Other names: Clostridium proteolyticum DSM 3090, H. proteolytica DSM 3090, Hathewaya proteolytica DSM 3090
Server load: low (20%) [HD]