STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmPhosphoglycerate mutase Gpm. (226 aa)    
Predicted Functional Partners:
AGC67662.1
Hypothetical protein.
  
   0.758
pyrD
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit PyrD; Catalyzes the conversion of dihydroorotate to orotate.
     
 0.705
pyrK
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit PyrK; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
 
  0.677
serC
Phosphoserine aminotransferase SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
    
 0.647
Ffh1
Hydrogenase large subunit domain protein.
 
     0.620
AGC67657.1
Hypothetical protein.
 
     0.608
AGC67654.1
DRTGG domain protein.
 
     0.589
glyA
Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.562
rsmF
Ribosomal RNA small subunit methyltransferase F.
   
   0.560
AGC67658.1
PHP domain protein.
       0.556
Your Current Organism:
Thermoclostridium stercorarium
NCBI taxonomy Id: 1121335
Other names: Clostridium stercorarium subsp. stercorarium DSM 8532, T. stercorarium subsp. stercorarium DSM 8532, Thermoclostridium stercorarium subsp. stercorarium DSM 8532
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