node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGC67776.1 | glyA | Cst_c07720 | Cst_c07730 | Hypothetical protein. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.686 |
AGC67776.1 | rluB | Cst_c07720 | Cst_c07710 | Hypothetical protein. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.773 |
AGC67776.1 | yebA | Cst_c07720 | Cst_c07700 | Hypothetical protein. | Transglutaminase domain protein YebA. | 0.410 |
AGC67901.1 | yebA | Cst_c09030 | Cst_c07700 | Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S). | Transglutaminase domain protein YebA. | 0.443 |
AGC68313.1 | yebA | Cst_c13220 | Cst_c07700 | Sortase family protein. | Transglutaminase domain protein YebA. | 0.450 |
AGC68324.1 | yebA | Cst_c13330 | Cst_c07700 | Response regulator receiver and SARP domain protein. | Transglutaminase domain protein YebA. | 0.672 |
glyA | AGC67776.1 | Cst_c07730 | Cst_c07720 | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein. | 0.686 |
glyA | icd | Cst_c07730 | Cst_c07690 | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.523 |
glyA | leuC1 | Cst_c07730 | Cst_c07680 | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 3-isopropylmalate dehydratase large subunit 1. | 0.484 |
glyA | rluB | Cst_c07730 | Cst_c07710 | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.695 |
glyA | yebA | Cst_c07730 | Cst_c07700 | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transglutaminase domain protein YebA. | 0.401 |
icd | glyA | Cst_c07690 | Cst_c07730 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.523 |
icd | leuC1 | Cst_c07690 | Cst_c07680 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 3-isopropylmalate dehydratase large subunit 1. | 0.998 |
icd | yebA | Cst_c07690 | Cst_c07700 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Transglutaminase domain protein YebA. | 0.444 |
leuC1 | glyA | Cst_c07680 | Cst_c07730 | 3-isopropylmalate dehydratase large subunit 1. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.484 |
leuC1 | icd | Cst_c07680 | Cst_c07690 | 3-isopropylmalate dehydratase large subunit 1. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.998 |
leuC1 | yebA | Cst_c07680 | Cst_c07700 | 3-isopropylmalate dehydratase large subunit 1. | Transglutaminase domain protein YebA. | 0.462 |
rluB | AGC67776.1 | Cst_c07710 | Cst_c07720 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | Hypothetical protein. | 0.773 |
rluB | glyA | Cst_c07710 | Cst_c07730 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.695 |
rluB | yebA | Cst_c07710 | Cst_c07700 | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | Transglutaminase domain protein YebA. | 0.410 |