node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gpr | spo0A1 | Cst_c05400 | Cst_c10970 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.788 |
gpr | spoIIAB | Cst_c05400 | Cst_c14090 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Anti-sigma F factor SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.809 |
gpr | spoIID | Cst_c05400 | Cst_c00830 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein D. | 0.420 |
gpr | spoIIE | Cst_c05400 | Cst_c25050 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein E. | 0.773 |
gpr | spoIIIAA | Cst_c05400 | Cst_c05310 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein AA. | 0.765 |
gpr | spoIIIAD1 | Cst_c05400 | Cst_c05340 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein AD. | 0.772 |
gpr | spoIIIAF | Cst_c05400 | Cst_c05370 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein AG. | 0.765 |
gpr | spoIIID | Cst_c05400 | Cst_c00850 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein D. | 0.769 |
gpr | spoIIR | Cst_c05400 | Cst_c23990 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein R. | 0.768 |
gpr | spoIVa | Cst_c05400 | Cst_c13160 | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage IV sporulation protein A. | 0.840 |
spo0A1 | gpr | Cst_c10970 | Cst_c05400 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Germination protease Gpr; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.788 |
spo0A1 | spoIIAB | Cst_c10970 | Cst_c14090 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.792 |
spo0A1 | spoIID | Cst_c10970 | Cst_c00830 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein D. | 0.412 |
spo0A1 | spoIIE | Cst_c10970 | Cst_c25050 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein E. | 0.807 |
spo0A1 | spoIIIAA | Cst_c10970 | Cst_c05310 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AA. | 0.813 |
spo0A1 | spoIIIAD1 | Cst_c10970 | Cst_c05340 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AD. | 0.747 |
spo0A1 | spoIIIAF | Cst_c10970 | Cst_c05370 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AG. | 0.682 |
spo0A1 | spoIIID | Cst_c10970 | Cst_c00850 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein D. | 0.824 |
spo0A1 | spoIIR | Cst_c10970 | Cst_c23990 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein R. | 0.813 |
spo0A1 | spoIVa | Cst_c10970 | Cst_c13160 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A. | 0.834 |