node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
birA | cinA | Cst_c26740 | Cst_c22410 | Bifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative competence-damage inducible protein CinA; Belongs to the CinA family. | 0.482 |
birA | nadA | Cst_c26740 | Cst_c15870 | Bifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.608 |
birA | nadB1 | Cst_c26740 | Cst_c27170 | Bifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | L-aspartate oxidase 1; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.617 |
birA | nadC | Cst_c26740 | Cst_c27160 | Bifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Nicotinate-nucleotide pyrophosphorylase; Carboxylating; Belongs to the NadC/ModD family. | 0.567 |
birA | nadE | Cst_c26740 | Cst_c15300 | Bifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Glutamine-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.817 |
cinA | birA | Cst_c22410 | Cst_c26740 | Putative competence-damage inducible protein CinA; Belongs to the CinA family. | Bifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.482 |
cinA | nadA | Cst_c22410 | Cst_c15870 | Putative competence-damage inducible protein CinA; Belongs to the CinA family. | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.611 |
cinA | nadC | Cst_c22410 | Cst_c27160 | Putative competence-damage inducible protein CinA; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase; Carboxylating; Belongs to the NadC/ModD family. | 0.964 |
cinA | nadE | Cst_c22410 | Cst_c15300 | Putative competence-damage inducible protein CinA; Belongs to the CinA family. | Glutamine-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.813 |
cysE | nadA | Cst_c02640 | Cst_c15870 | Serine acetyltransferase CysE. | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.886 |
cysE | nadE | Cst_c02640 | Cst_c15300 | Serine acetyltransferase CysE. | Glutamine-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.404 |
dapA | infB | Cst_c11900 | Cst_c10890 | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.430 |
dapA | nadA | Cst_c11900 | Cst_c15870 | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.640 |
gmk | infB | Cst_c20230 | Cst_c10890 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.502 |
gmk | nadA | Cst_c20230 | Cst_c15870 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.726 |
infB | dapA | Cst_c10890 | Cst_c11900 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.430 |
infB | gmk | Cst_c10890 | Cst_c20230 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | 0.502 |
infB | nadA | Cst_c10890 | Cst_c15870 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.583 |
infB | nadE | Cst_c10890 | Cst_c15300 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Glutamine-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.469 |
infB | valS | Cst_c10890 | Cst_c21360 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | valine--tRNA ligase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.713 |