node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
sigG | spo0A1 | Cst_c15540 | Cst_c10970 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.808 |
sigG | spoIIAB | Cst_c15540 | Cst_c14090 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.847 |
sigG | spoIIE | Cst_c15540 | Cst_c25050 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein E. | 0.866 |
sigG | spoIIGA | Cst_c15540 | Cst_c15560 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.902 |
sigG | spoIIIAA | Cst_c15540 | Cst_c05310 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein AA. | 0.763 |
sigG | spoIIIAF | Cst_c15540 | Cst_c05370 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein AG. | 0.741 |
sigG | spoIIID | Cst_c15540 | Cst_c00850 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D. | 0.802 |
sigG | spoIIR | Cst_c15540 | Cst_c23990 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein R. | 0.818 |
sigG | spoIVa | Cst_c15540 | Cst_c13160 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A. | 0.804 |
sigG | spoVT | Cst_c15540 | Cst_c24960 | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein T. | 0.791 |
spo0A1 | sigG | Cst_c10970 | Cst_c15540 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | RNA polymerase sigma-G factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.808 |
spo0A1 | spoIIAB | Cst_c10970 | Cst_c14090 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.792 |
spo0A1 | spoIIE | Cst_c10970 | Cst_c25050 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein E. | 0.807 |
spo0A1 | spoIIGA | Cst_c10970 | Cst_c15560 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Sporulation sigma-E factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.618 |
spo0A1 | spoIIIAA | Cst_c10970 | Cst_c05310 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AA. | 0.813 |
spo0A1 | spoIIIAF | Cst_c10970 | Cst_c05370 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AG. | 0.682 |
spo0A1 | spoIIID | Cst_c10970 | Cst_c00850 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein D. | 0.824 |
spo0A1 | spoIIR | Cst_c10970 | Cst_c23990 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein R. | 0.813 |
spo0A1 | spoIVa | Cst_c10970 | Cst_c13160 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A. | 0.834 |
spo0A1 | spoVT | Cst_c10970 | Cst_c24960 | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage V sporulation protein T. | 0.825 |