STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC27880.1Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA. (147 aa)    
Predicted Functional Partners:
SMC27883.1
Aminomethyltransferase; Belongs to the GcvT family.
 
     0.840
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
 
 0.748
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
 0.706
gcvPA
Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
       0.698
SMC27891.1
Glycine dehydrogenase (decarboxylating) beta subunit.
       0.698
SMC24453.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.663
SMC27717.1
Uroporphyrinogen III methyltransferase / synthase.
  
 
 0.655
SMC27386.1
L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.627
SMC20250.1
Regulatory protein, luxR family.
 
 
 0.576
SMC27910.1
L-alanine dehydrogenase; Belongs to the AlaDH/PNT family.
     
 0.513
Your Current Organism:
Desulfacinum hydrothermale
NCBI taxonomy Id: 1121390
Other names: D. hydrothermale DSM 13146, Desulfacinum hydrothermale DSM 13146
Server load: low (28%) [HD]