STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (569 aa)    
Predicted Functional Partners:
SHH91821.1
3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family.
 
 
 0.982
SHH38922.1
Branched chain amino acid aminotransferase apoenzyme.
  
 0.964
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.964
SHH91833.1
3-isopropylmalate dehydratase, large subunit; Belongs to the aconitase/IPM isomerase family.
 
 0.964
SHH90074.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.962
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 0.953
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.937
SHH46459.1
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit.
 
 0.928
SHI04388.1
Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase.
  
 0.914
SHH46061.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.903
Your Current Organism:
Desulfofustis glycolicus
NCBI taxonomy Id: 1121409
Other names: D. glycolicus DSM 9705, Desulfofustis glycolicus DSM 9705
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