STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHO42721.1Sugar or nucleoside kinase, ribokinase family. (338 aa)    
Predicted Functional Partners:
SHO42723.1
Hypothetical protein.
  
 
 0.896
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.802
SHO42725.1
Fructokinase.
    
 0.794
SHO52411.1
Threonine dehydrogenase.
 
 
 0.792
SHO51843.1
LPS sulfotransferase NodH.
  
 0.788
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.757
SHO51014.1
Mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.756
SHO47947.1
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family.
 
  
 0.752
SHO49344.1
Transketolase, C-terminal subunit.
    
 0.743
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.741
Your Current Organism:
Desulfopila aestuarii
NCBI taxonomy Id: 1121416
Other names: D. aestuarii DSM 18488, Desulfopila aestuarii DSM 18488
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