STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHO49635.1Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)    
Predicted Functional Partners:
SHO52687.1
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.974
SHO49636.1
Aconitase; Belongs to the aconitase/IPM isomerase family.
  
 
 0.971
SHO44394.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 
 0.962
SHO47338.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.962
SHO44067.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.951
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.951
SHO48827.1
Uncharacterized iron-regulated protein.
    
 0.944
SHO48866.1
NADPH-dependent glutamate synthase beta chain.
   
 
 0.927
SHO50200.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.914
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.909
Your Current Organism:
Desulfopila aestuarii
NCBI taxonomy Id: 1121416
Other names: D. aestuarii DSM 18488, Desulfopila aestuarii DSM 18488
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