STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHJ32394.1Hypothetical protein. (57 aa)    
Predicted Functional Partners:
SHJ32372.1
Hypothetical protein.
       0.695
SHJ21104.1
Hypothetical protein.
  
     0.688
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.635
SHJ32442.1
Nitrogen fixation protein NifU.
       0.608
SHI94710.1
Putative sporulation protein YtaF; Probably functions as a manganese efflux pump.
  
     0.596
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
       0.589
SHJ32502.1
Transcriptional regulator, BadM/Rrf2 family.
       0.577
SHJ38692.1
Hypothetical protein.
  
     0.555
SHJ28472.1
Protein of unknown function.
  
     0.535
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.526
Your Current Organism:
Desulfofundulus thermosubterraneus
NCBI taxonomy Id: 1121432
Other names: D. thermosubterraneus DSM 16057, Desulfofundulus thermosubterraneus DSM 16057, Desulfotomaculum thermosubterraneum DSM 16057
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