STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_0176PFAM: peptidase M48 Ste24p; KEGG: adk:Alide2_2056 peptidase M48 Ste24p. (321 aa)    
Predicted Functional Partners:
dsat_0175
PDZ/DHR/GLGF domain protein; KEGG: adk:Alide2_2055 peptidase S1 and S6 chymotrypsin/Hap; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
  
 0.913
dsat_0177
PFAM: Phosphate-starvation-inducible E-like protein; KEGG: adk:Alide2_2057 hypothetical protein.
 
     0.883
ftsH
Peptidase M41 FtsH domain protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
 
 0.749
dsat_0181
KEGG: adk:Alide2_2061 ATPase AAA-2 domain-containing protein; PFAM: ATPase AAA-2 domain protein, Clp ATPase domain-containing protein, AAA ATPase central domain protein, Clp domain protein; SMART: Clp ATPase domain-containing protein, AAA ATPase; Belongs to the ClpA/ClpB family.
 
  
 0.670
dsat_0178
PFAM: heat shock protein Hsp20; KEGG: rpf:Rpic12D_0623 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
 
  
 0.669
dsat_1510
KEGG: das:Daes_1512 flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM, surface presentation of antigens (SPOA) protein.
    
   0.618
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.571
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.535
ftsH-2
Peptidase M41 FtsH domain protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.514
dsat_0540
PFAM: protein of unknown function UPF0005; KEGG: dma:DMR_44900 hypothetical membrane protein; Belongs to the BI1 family.
  
  
 0.513
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.