STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (254 aa)    
Predicted Functional Partners:
dsat_0421
PFAM: Indole-3-glycerol phosphate synthase; KEGG: dma:DMR_05280 indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 
 0.999
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
trpF
KEGG: dvm:DvMF_1742 phosphoribosylanthranilate isomerase; HAMAP : N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5 phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.997
trpB-2
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.996
dsat_0419
KEGG: das:Daes_0950 glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase type 1.
 
 
 0.994
dsat_0418
PFAM: Chorismate binding domain-containing protein, Anthranilate synthase component I domain protein; KEGG: dma:DMR_05320 anthranilate synthase component I.
 
  
 0.986
dsat_1670
PFAM: Glutamine amidotransferase type 1; KEGG: das:Daes_3325 glutamine amidotransferase.
 
 
 0.982
trpF-2
KEGG: drt:Dret_0255 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); HAMAP : N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5 phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 
 0.974
dsat_1671
PFAM: Chorismate binding domain-containing protein; KEGG: das:Daes_3324 chorismate-binding-like protein.
 
  
 0.949
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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