STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (409 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
dsat_0458
KEGG: drt:Dret_1421 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding domain.
 0.999
dsat_0459
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 0.999
dsat_0581
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
   
 0.971
dsat_1112
KEGG: dsa:Desal_1152 flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: Flagellar motor switch protein FliG, C-terminal, MgtE intracellular region.
    
 
 0.960
dsat_0847
PFAM: response regulator receiver; KEGG: dma:DMR_02840 putative chemotaxis protein CheY.
   
 0.958
dsat_2416
KEGG: sta:STHERM_c02220 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver.
    
 0.955
dsat_0670
PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein, PAS fold-4 domain protein, PAS fold domain protein, histidine kinase A domain protein; KEGG: das:Daes_0516 PAS sensor protein; SMART: ATP-binding region ATPase domain protein, histidine kinase A domain protein, PAS domain containing protein.
    
 0.954
dsat_2115
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein, histidine kinase A domain protein, PAS fold domain protein, response regulator receiver; KEGG: das:Daes_2894 PAS sensor protein; SMART: ATP-binding region ATPase domain protein, PAS domain containing protein, histidine kinase A domain protein.
    
 0.954
dsat_2100
Diguanylate cyclase/phosphodiesterase with PAS/PAC and integral membrane sensor(s); TIGRFAM: diguanylate cyclase, PAS sensor protein; PFAM: EAL domain-containing protein, PAS fold domain protein, CHASE4 domain protein, GGDEF domain containing protein, histidine kinase HAMP region domain protein; KEGG: dba:Dbac_2629 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; SMART: EAL domain-containing protein, GGDEF domain containing protein, PAS domain containing protein.
    
 0.951
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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