STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_0631Diguanylate cyclase with integral membrane sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein, Cache domain protein, histidine kinase HAMP region domain protein; KEGG: dsa:Desal_0263 diguanylate cyclase; SMART: GGDEF domain containing protein. (546 aa)    
Predicted Functional Partners:
dsat_2438
KEGG: dma:DMR_02640 OmpR family two-component response regulator; PFAM: response regulator receiver, transcriptional regulator domain-containing protein; SMART: response regulator receiver, transcriptional regulator domain-containing protein.
 
 
 
  0.904
dsat_1649
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein, GAF domain protein, ATP-binding region ATPase domain protein; KEGG: dma:DMR_27220 two-component hybrid sensor and regulator; SMART: ATP-binding region ATPase domain protein, PAC repeat-containing protein, PAS domain containing protein, histidine kinase A domain protein, GAF domain protein.
 
 0.903
dsat_2854
SMART: metal-dependent phosphohydrolase HD region; KEGG: dma:DMR_28350 hypothetical protein.
 
 
  0.900
dsat_0889
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein, Hpt domain protein; KEGG: dma:DMR_25470 two-component hybrid sensor and regulator; SMART: response regulator receiver, ATP-binding region ATPase domain protein, PAS domain containing protein, histidine kinase A domain protein.
 
 0.875
dsat_2416
KEGG: sta:STHERM_c02220 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 0.873
dsat_0426
Integral membrane sensor hybrid histidine kinase; KEGG: sta:STHERM_c16510 autoinducer 2 sensor kinase/phosphatase LuxQ; PFAM: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver; SMART: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver.
 
 0.871
dsat_0669
PFAM: Hpt domain protein; KEGG: tmz:Tmz1t_1730 multi-sensor hybrid histidine kinase.
  
 0.871
dsat_1105
TIGRFAM: diguanylate cyclase; PFAM: EAL domain-containing protein, GGDEF domain containing protein, PAS fold-4 domain protein; KEGG: dma:DMR_13960 GGDEF domain protein; SMART: EAL domain-containing protein, GGDEF domain containing protein.
0.870
dsat_0961
Diguanylate cyclase with PAS/PAC and GAF sensor; TIGRFAM: diguanylate cyclase, PAS sensor protein; PFAM: GGDEF domain containing protein, response regulator receiver, PAS domain containing protein; KEGG: tmz:Tmz1t_2654 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: GGDEF domain containing protein, PAS domain containing protein, GAF domain protein.
 
0.867
dsat_0259
KEGG: dba:Dbac_2101 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver; SMART: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver.
 
 0.865
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.