STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheB-2Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (361 aa)    
Predicted Functional Partners:
dsat_0947
KEGG: dsa:Desal_2724 CheA signal transduction histidine kinase; PFAM: CheW domain protein, Hpt domain protein, Signal transducing histidine kinase homodimeric, ATP-binding region ATPase domain protein; SMART: CheW domain protein, ATP-binding region ATPase domain protein, Hpt domain protein.
 
 0.992
dsat_0942
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.990
dsat_0873
KEGG: gme:Gmet_2427 CheA signal transduction histidine kinase; PFAM: CheW domain protein, Hpt domain protein, ATP-binding region ATPase domain protein, Signal transducing histidine kinase homodimeric; SMART: CheW domain protein, ATP-binding region ATPase domain protein, Hpt domain protein.
 
 0.989
dsat_0874
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.983
dsat_2033
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.982
dsat_0581
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
0.979
dsat_0945
CheW protein; KEGG: dsa:Desal_2726 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 
 0.971
dsat_1586
CheW protein; KEGG: dvm:DvMF_0284 chemotaxis protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 
 0.970
dsat_1374
KEGG: das:Daes_1693 CheW domain-containing protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 
 0.968
dsat_2675
KEGG: dvm:DvMF_2021 chemotaxis protein CheW; PFAM: CheW domain protein, response regulator receiver; SMART: CheW domain protein, response regulator receiver.
 
 0.959
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
Server load: low (18%) [HD]