STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pyrFOrotidine 5'-phosphate decarboxylase subfamily 1 core; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (233 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.990
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.985
pyrR
Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.961
pyrB
TIGRFAM: aspartate carbamoyltransferase; HAMAP : Aspartate carbamoyltransferase; KEGG: das:Daes_3196 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain-containing protein, aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.959
pyrC
Dihydroorotase multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
  
 0.958
carB
SMART: Carbamoyl-phosphate synthetase large chain oligomerisation, MGS domain protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; KEGG: drt:Dret_0320 carbamoyl-phosphate synthase, large subunit; HAMAP : Carbamoyl-phosphate synthase large subunit glutamine-dependent; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding protein, Carbamoyl-phosphate synthetase large chain oligomerisation, Carbamoyl-phosphate synthetase large chain domain protein, MGS domain protein; Belongs to the CarB family.
  
  
 0.953
carA
SMART: Carbamoyl-phosphate synthase small chain; TIGRFAM: carbamoyl-phosphate synthase, small subunit; KEGG: dma:DMR_20320 carbamoyl phosphate synthase small subunit; HAMAP : Carbamoyl-phosphate synthase small chain; PFAM: Carbamoyl-phosphate synthase small chain, Glutamine amidotransferase type 1; Belongs to the CarA family.
  
  
 0.947
dsat_1035
KEGG: dsa:Desal_1578 uracil-xanthine permease; TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease.
  
  
 0.890
dsat_0576
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein, Oxidoreductase FAD-binding domain protein, Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain-containing protein; KEGG: dma:DMR_01960 putative oxidoreductase.
  
 
 0.866
dsat_0580
PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain-containing protein, oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dvl:Dvul_0767 ferredoxin-NADP(+) reductase subunit alpha.
  
 
 0.866
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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