STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_1194KEGG: dma:DMR_43700 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type; SMART: Transcription regulator, AsnC-type. (154 aa)    
Predicted Functional Partners:
dsat_1193
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.873
dsat_2101
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein.
    
 0.772
sucD
ATP-grasp domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
 0.705
dsat_2284
2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: das:Daes_1447 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase.
    
  0.690
dsat_0261
KEGG: dsa:Desal_0251 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4, Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
  
 
 0.563
dsat_0358
CoA-binding domain protein; KEGG: dba:Dbac_1477 GCN5-like N-acetyltransferase; PFAM: CoA-binding domain protein, GCN5-related N-acetyltransferase; SMART: CoA-binding domain protein.
    
  0.448
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
    0.444
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 0.420
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.