STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_2008PFAM: heat shock protein Hsp20; KEGG: dma:DMR_15920 heat shock protein HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. (153 aa)    
Predicted Functional Partners:
dsat_2420
PFAM: heat shock protein Hsp20; KEGG: dma:DMR_11460 heat shock protein HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
 
    0.808
dsat_0181
KEGG: adk:Alide2_2061 ATPase AAA-2 domain-containing protein; PFAM: ATPase AAA-2 domain protein, Clp ATPase domain-containing protein, AAA ATPase central domain protein, Clp domain protein; SMART: Clp ATPase domain-containing protein, AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.599
dsat_0880
TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein, AAA ATPase central domain protein, Clp ATPase domain-containing protein, Clp domain protein; KEGG: dma:DMR_23720 ATP-dependent Clp protease ATP-binding subunit ClpA; SMART: Clp ATPase domain-containing protein, AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.599
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.599
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.557
aroK-2
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
   
   0.531
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
  
 
 0.528
dsat_0178
PFAM: heat shock protein Hsp20; KEGG: rpf:Rpic12D_0623 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
     0.508
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.499
dsat_2009
RNA methylase; KEGG: dde:Dde_1488 hypothetical protein; PFAM: RNA methylase; SMART: THUMP domain-containing protein; Belongs to the methyltransferase superfamily.
       0.481
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.