STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (135 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.860
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.809
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.681
dsat_1645
Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase, PAS sensor protein; PFAM: GGDEF domain containing protein, PAS fold-3 domain protein, response regulator receiver, histidine kinase A domain protein; KEGG: dma:DMR_34900 putative two-component hybrid sensor and regulator; SMART: GGDEF domain containing protein, histidine kinase A domain protein, response regulator receiver, PAS domain containing protein.
     
 0.523
dsat_0306
Response regulator receiver protein; KEGG: sur:STAUR_6958 sensor protein; PFAM: ATP-binding region ATPase domain protein, response regulator receiver; SMART: response regulator receiver, ATP-binding region ATPase domain protein.
     
 0.491
dsat_1627
PFAM: sodium/hydrogen exchanger, TrkA-N domain protein; KEGG: drt:Dret_1189 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.483
pyrB
TIGRFAM: aspartate carbamoyltransferase; HAMAP : Aspartate carbamoyltransferase; KEGG: das:Daes_3196 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain-containing protein, aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
    0.437
dsat_2149
PFAM: phosphoesterase RecJ domain protein; KEGG: dvm:DvMF_1755 phosphoesterase RecJ domain protein.
       0.429
dsat_2151
KEGG: das:Daes_2488 hypothetical protein.
       0.423
dsat_2150
Cobalbumin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
       0.405
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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