STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_2197KEGG: dma:DMR_35930 hypothetical protein. (316 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.995
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.948
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.906
dsat_2196
KEGG: das:Daes_0134 DNA repair ATPase-like protein.
  
  
 0.853
dsat_1384
KEGG: das:Daes_1316 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding protein, Sulfate transporter/antisigma-factor antagonist STAS, sulfate transporter; SMART: cyclic nucleotide-binding protein.
  
   0.847
dsat_1105
TIGRFAM: diguanylate cyclase; PFAM: EAL domain-containing protein, GGDEF domain containing protein, PAS fold-4 domain protein; KEGG: dma:DMR_13960 GGDEF domain protein; SMART: EAL domain-containing protein, GGDEF domain containing protein.
    
 0.837
dsat_2572
PFAM: sulfate transporter, Sulfate transporter/antisigma-factor antagonist STAS; KEGG: das:Daes_0067 sulfate transporter.
   
   0.836
dsat_2828
KEGG: dde:Dde_0177 DNA polymerase III subunit delta'.
   
 0.828
dsat_0909
KEGG: dvm:DvMF_0171 beta-lactamase; PFAM: Beta-Casp domain, beta-lactamase domain protein, RNA-metabolising metallo-beta-lactamase; SMART: Beta-Casp domain, beta-lactamase domain protein.
  
 0.812
dsat_2198
KEGG: das:Daes_0136 hypothetical protein.
       0.803
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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