STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
folE2GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. (260 aa)    
Predicted Functional Partners:
dsat_1745
Queuosine biosynthesis protein QueD; KEGG: dde:Dde_2197 6-pyruvoyl tetrahydrobiopterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein.
 
  
 0.914
dsat_1649
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein, GAF domain protein, ATP-binding region ATPase domain protein; KEGG: dma:DMR_27220 two-component hybrid sensor and regulator; SMART: ATP-binding region ATPase domain protein, PAC repeat-containing protein, PAS domain containing protein, histidine kinase A domain protein, GAF domain protein.
    
  0.826
dsat_1547
KEGG: dvm:DvMF_0362 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
    
 0.799
dsat_2319
KEGG: dma:DMR_17830 hypothetical protein; PFAM: cobalamin synthesis protein P47K, cobalamin synthesis CobW domain protein; SMART: cobalamin synthesis CobW domain protein.
  
  
 0.789
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.743
dsat_0721
PFAM: Molybdenum cofactor carrier, putative; KEGG: glo:Glov_0284 hypothetical protein.
 
  
 0.735
dsat_2603
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.732
dsat_0426
Integral membrane sensor hybrid histidine kinase; KEGG: sta:STHERM_c16510 autoinducer 2 sensor kinase/phosphatase LuxQ; PFAM: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver; SMART: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver.
    
  0.731
dsat_1168
Hpt protein; KEGG: dde:Dde_1668 sensory box histidine kinase/response regulator; PFAM: Hpt domain protein; SMART: Hpt domain protein.
    
  0.730
dsat_2209
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein, PAS fold-4 domain protein; KEGG: dsa:Desal_3332 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein, histidine kinase A domain protein, PAS domain containing protein, response regulator receiver.
    
  0.730
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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