STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_2626PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: dsa:Desal_1532 pyruvate ferredoxin/flavodoxin oxidoreductase. (74 aa)    
Predicted Functional Partners:
dsat_2101
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein.
  
 0.997
sucD
ATP-grasp domain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.832
dsat_1014
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: dba:Dbac_0089 thiamine pyrophosphate protein domain-containing protein.
  
 0.818
dsat_2283
KEGG: drt:Dret_0516 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
  
 0.818
dsat_2778
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: das:Daes_3335 thiamine pyrophosphate TPP-binding domain-containing protein.
  
 0.818
dsat_2625
KEGG: dde:Dde_1635 Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein, helix-turn-helix Fis-type, GAF domain protein; SMART: AAA ATPase, GAF domain protein.
       0.791
dsat_2574
PFAM: 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; KEGG: dvm:DvMF_2713 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
 0.789
dsat_2105
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.757
dsat_0358
CoA-binding domain protein; KEGG: dba:Dbac_1477 GCN5-like N-acetyltransferase; PFAM: CoA-binding domain protein, GCN5-related N-acetyltransferase; SMART: CoA-binding domain protein.
    
 0.727
dsat_1013
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Transketolase domain-containing protein; KEGG: dba:Dbac_0088 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 0.697
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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