node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dsat_0459 | dsat_1091 | dsat_0459 | dsat_1091 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | 0.450 |
dsat_0459 | dsat_2727 | dsat_0459 | dsat_2727 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | 0.837 |
dsat_0459 | dsat_2893 | dsat_0459 | dsat_2893 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase, Riboflavin kinase; KEGG: das:Daes_0874 riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; Belongs to the ribF family. | 0.760 |
dsat_0459 | guaA | dsat_0459 | dsat_1042 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.661 |
dsat_0459 | guaB | dsat_0459 | dsat_1043 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.739 |
dsat_0459 | ribH | dsat_0459 | dsat_0456 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
dsat_1091 | dsat_0459 | dsat_1091 | dsat_0459 | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.450 |
dsat_1091 | dsat_1860 | dsat_1091 | dsat_1860 | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | PFAM: FAD linked oxidase domain-containing protein, protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein, FAD linked oxidase domain protein; KEGG: drt:Dret_1131 FAD linked oxidase domain-containing protein. | 0.722 |
dsat_1091 | dsat_2727 | dsat_1091 | dsat_2727 | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | 0.731 |
dsat_1091 | dsat_2729 | dsat_1091 | dsat_2729 | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | KEGG: dvm:DvMF_1790 CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.618 |
dsat_1091 | guaA | dsat_1091 | dsat_1042 | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.785 |
dsat_1091 | guaB | dsat_1091 | dsat_1043 | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.789 |
dsat_1860 | dsat_1091 | dsat_1860 | dsat_1091 | PFAM: FAD linked oxidase domain-containing protein, protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein, FAD linked oxidase domain protein; KEGG: drt:Dret_1131 FAD linked oxidase domain-containing protein. | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | 0.722 |
dsat_1860 | dsat_2727 | dsat_1860 | dsat_2727 | PFAM: FAD linked oxidase domain-containing protein, protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein, FAD linked oxidase domain protein; KEGG: drt:Dret_1131 FAD linked oxidase domain-containing protein. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | 0.696 |
dsat_2509 | dsat_2727 | dsat_2509 | dsat_2727 | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, phosphoglucomutase/phosphomannomutase, phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: dma:DMR_27100 phosphohexose mutase. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | 0.656 |
dsat_2509 | guaA | dsat_2509 | dsat_1042 | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, phosphoglucomutase/phosphomannomutase, phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: dma:DMR_27100 phosphohexose mutase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.418 |
dsat_2509 | guaB | dsat_2509 | dsat_1043 | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I, phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III, phosphoglucomutase/phosphomannomutase, phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: dma:DMR_27100 phosphohexose mutase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.432 |
dsat_2727 | dsat_0459 | dsat_2727 | dsat_0459 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.837 |
dsat_2727 | dsat_1091 | dsat_2727 | dsat_1091 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | KEGG: mrd:Mrad2831_2101 alpha/beta hydrolase fold. | 0.731 |
dsat_2727 | dsat_1860 | dsat_2727 | dsat_1860 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; KEGG: drt:Dret_1023 HAD-superfamily hydrolase, subfamily IA, variant 3. | PFAM: FAD linked oxidase domain-containing protein, protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein, FAD linked oxidase domain protein; KEGG: drt:Dret_1131 FAD linked oxidase domain-containing protein. | 0.696 |