STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsat_2736Mutator MutT protein; KEGG: das:Daes_1311 NUDIX hydrolase; TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase. (135 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.803
dsat_2734
KEGG: das:Daes_1310 ABC transporter-like protein; PFAM: ABC transporter related protein; SMART: AAA ATPase.
       0.793
dsat_2735
KEGG: dma:DMR_03410 hypothetical protein.
       0.773
dsat_2271
KEGG: das:Daes_3132 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase, dihydropteroate synthase DHPS, cobalamin B12-binding domain protein, Methionine synthase B12-binding module cap domain protein; SMART: Methionine synthase B12-binding module cap domain protein.
    
 0.761
dsat_2101
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein.
    
 0.754
dsat_2737
KEGG: das:Daes_1312 methylenetetrahydrofolate reductase (NAD(P)H); TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.722
dsat_1649
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein, GAF domain protein, ATP-binding region ATPase domain protein; KEGG: dma:DMR_27220 two-component hybrid sensor and regulator; SMART: ATP-binding region ATPase domain protein, PAC repeat-containing protein, PAS domain containing protein, histidine kinase A domain protein, GAF domain protein.
  
 
  0.720
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.712
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.696
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.693
Your Current Organism:
Desulfovibrio alkalitolerans
NCBI taxonomy Id: 1121439
Other names: D. alkalitolerans DSM 16529, Desulfovibrio alkalitolerans DSM 16529
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