STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)    
Predicted Functional Partners:
sucD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.980
SIO08720.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.918
SIO38585.1
Fumarate reductase flavoprotein subunit.
 
 0.904
SIO12916.1
Fumarate reductase flavoprotein subunit.
 
 0.902
SIO18442.1
Dissimilatory adenylylsulfate reductase alpha subunit precursor.
  
 0.874
SIO28132.1
FAD dependent oxidoreductase.
  
 0.847
SIN71341.1
NAD(P)H dehydrogenase (quinone).
  
 0.842
SIN89612.1
Isocitrate dehydrogenase (NADP).
   
 0.828
SIO12895.1
Fumarate reductase iron-sulfur subunit.
  
 0.825
SIO38600.1
Fumarate reductase iron-sulfur subunit.
  
 0.825
Your Current Organism:
Halodesulfovibrio marinisediminis
NCBI taxonomy Id: 1121457
Other names: Desulfovibrio marinisediminis C/L2, Desulfovibrio marinisediminis DSM 17456, Desulfovibrio marinisediminis JCM 14577, Desulfovibrio sp. C/L2, Desulfovibrio sp. JCM 14577, H. marinisediminis DSM 17456, Halodesulfovibrio marinisediminis DSM 17456, Halodesulfovibrio marinisediminis JCM 14577
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