STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIO12843.1Fumarate hydratase subunit beta. (181 aa)    
Predicted Functional Partners:
SIO12876.1
Fumarase, class I alpha subunit.
 
 0.998
SIO38616.1
Fumarase, class I alpha subunit.
 
 0.995
SIO12895.1
Fumarate reductase iron-sulfur subunit.
  
 
 0.922
SIO12916.1
Fumarate reductase flavoprotein subunit.
  
 
 0.920
sucD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.871
SIO12934.1
Succinate dehydrogenase subunit C.
  
 
 0.851
SIO12826.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
 
 
 0.831
SIN89612.1
Isocitrate dehydrogenase (NADP).
  
  
 0.695
SIO11988.1
Fe-S oxidoreductase.
     
 0.695
SIO26544.1
Glycine dehydrogenase (decarboxylating) beta subunit.
   
    0.681
Your Current Organism:
Halodesulfovibrio marinisediminis
NCBI taxonomy Id: 1121457
Other names: Desulfovibrio marinisediminis C/L2, Desulfovibrio marinisediminis DSM 17456, Desulfovibrio marinisediminis JCM 14577, Desulfovibrio sp. C/L2, Desulfovibrio sp. JCM 14577, H. marinisediminis DSM 17456, Halodesulfovibrio marinisediminis DSM 17456, Halodesulfovibrio marinisediminis JCM 14577
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.