STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (963 aa)    
Predicted Functional Partners:
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
 
 0.987
pdhC2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.981
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
 
 0.980
lpdG
Dihydrolipoyl dehydrogenase.
  
 
 0.917
pdhD1
Dihydrolipoyl dehydrogenase.
 
 
 0.901
FEAC_09470
NAD-dependent malic enzyme.
    
 0.885
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.880
ilvH
Putative acetolactate synthase small subunit.
     
 0.861
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
     
 0.853
aarA
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.850
Your Current Organism:
Ferrimicrobium acidiphilum
NCBI taxonomy Id: 1121877
Other names: F. acidiphilum DSM 19497, Ferrimicrobium acidiphilum DSM 19497
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