node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEAC_23620 | aroA1 | FEAC_23620 | FEAC_22230 | Prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.939 |
FEAC_23620 | aroB | FEAC_23620 | FEAC_24860 | Prephenate dehydrogenase. | 3-dehydroquinate synthase. | 0.885 |
FEAC_23620 | aroC | FEAC_23620 | FEAC_24850 | Prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.976 |
FEAC_23620 | aroE | FEAC_23620 | FEAC_02980 | Prephenate dehydrogenase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.700 |
FEAC_23620 | aroH2 | FEAC_23620 | FEAC_22240 | Prephenate dehydrogenase. | Chorismate mutase AroH. | 0.876 |
FEAC_23620 | aroK3 | FEAC_23620 | FEAC_24690 | Prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.866 |
FEAC_23620 | aroQ | FEAC_23620 | FEAC_24870 | Prephenate dehydrogenase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.484 |
FEAC_23620 | pchA | FEAC_23620 | FEAC_13600 | Prephenate dehydrogenase. | Salicylate biosynthesis isochorismate synthase. | 0.517 |
FEAC_23620 | pheA1 | FEAC_23620 | FEAC_16420 | Prephenate dehydrogenase. | Prephenate dehydratase. | 0.956 |
FEAC_23620 | trpE | FEAC_23620 | FEAC_23360 | Prephenate dehydrogenase. | Anthranilate synthase component 1. | 0.681 |
aroA1 | FEAC_23620 | FEAC_22230 | FEAC_23620 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydrogenase. | 0.939 |
aroA1 | aroB | FEAC_22230 | FEAC_24860 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase. | 0.998 |
aroA1 | aroC | FEAC_22230 | FEAC_24850 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
aroA1 | aroE | FEAC_22230 | FEAC_02980 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.997 |
aroA1 | aroH2 | FEAC_22230 | FEAC_22240 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate mutase AroH. | 0.880 |
aroA1 | aroK3 | FEAC_22230 | FEAC_24690 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.964 |
aroA1 | aroQ | FEAC_22230 | FEAC_24870 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.886 |
aroA1 | pchA | FEAC_22230 | FEAC_13600 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Salicylate biosynthesis isochorismate synthase. | 0.598 |
aroA1 | pheA1 | FEAC_22230 | FEAC_16420 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydratase. | 0.692 |
aroA1 | trpE | FEAC_22230 | FEAC_23360 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase component 1. | 0.507 |