STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FEAC_26140Nucleotidyltransferase domain protein. (132 aa)    
Predicted Functional Partners:
FEAC_26150
Hypothetical protein.
 
  
 0.966
FEAC_05060
Putative oxidoreductase/MSMEI_1564.
    
 0.903
FEAC_26210
Hypothetical protein.
 
  
 0.859
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
 0.853
FEAC_09470
NAD-dependent malic enzyme.
    
  0.834
metB
Cystathionine gamma-synthase.
  
 
 0.809
cdr2
Coenzyme A disulfide reductase.
    
  0.621
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.597
FEAC_12250
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.595
cysE
Serine acetyltransferase.
    
  0.576
Your Current Organism:
Ferrimicrobium acidiphilum
NCBI taxonomy Id: 1121877
Other names: F. acidiphilum DSM 19497, Ferrimicrobium acidiphilum DSM 19497
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.