STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHE72299.1(2S)-methylsuccinyl-CoA dehydrogenase. (534 aa)    
Predicted Functional Partners:
SHE42430.1
(R)-ethylmalonyl-CoA mutase.
 
 
 0.890
SHE51375.1
Electron transfer flavoprotein alpha subunit apoprotein.
 
  0.796
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.790
SHE38880.1
2-oxoglutarate dehydrogenase E1 component.
   
 0.752
SHE51398.1
Electron transfer flavoprotein beta subunit.
 
   0.743
SHE60716.1
Predicted kinase, aminoglycoside phosphotransferase (APT) family.
 
 
  0.731
SHE30694.1
L-proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.730
SHE27778.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
  0.727
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.712
SHE28160.1
Transcriptional regulator, XRE family with cupin sensor.
   
 
  0.707
Your Current Organism:
Ferrithrix thermotolerans
NCBI taxonomy Id: 1121881
Other names: F. thermotolerans DSM 19514, Ferrithrix thermotolerans DSM 19514
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