STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SJZ31563.1Phosphoribosylanthranilate isomerase. (164 aa)    
Predicted Functional Partners:
SJZ39404.1
Chorismate mutase.
  
 
 0.758
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.601
SJZ88627.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.587
SJZ74594.1
Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.573
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.564
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
  0.564
SJZ82367.1
Aspartate kinase; Belongs to the aspartokinase family.
    
 0.560
SJZ36519.1
Basic amino acid/polyamine antiporter, APA family.
    
 
 0.542
SJZ82391.1
Homoserine dehydrogenase.
    
 0.511
SJZ33186.1
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.501
Your Current Organism:
Globicatella sulfidifaciens
NCBI taxonomy Id: 1121925
Other names: G. sulfidifaciens DSM 15739, Globicatella sulfidifaciens DSM 15739
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.