node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ31959.1 | SJZ35590.1 | SAMN02746011_00244 | SAMN02746011_00479 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease, DNA polymerase III, epsilon subunit family. | 0.956 |
SJZ31959.1 | SJZ73013.1 | SAMN02746011_00244 | SAMN02746011_01620 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Superfamily I DNA and RNA helicases. | 0.791 |
SJZ31959.1 | SJZ77470.1 | SAMN02746011_00244 | SAMN02746011_01724 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.855 |
SJZ31959.1 | polA | SAMN02746011_00244 | SAMN02746011_01668 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
SJZ31959.1 | recA | SAMN02746011_00244 | SAMN02746011_00435 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.869 |
SJZ31959.1 | recD2 | SAMN02746011_00244 | SAMN02746011_00554 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease V alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.831 |
SJZ31959.1 | topA | SAMN02746011_00244 | SAMN02746011_00785 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.651 |
SJZ35590.1 | SJZ31959.1 | SAMN02746011_00479 | SAMN02746011_00244 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.956 |
SJZ35590.1 | SJZ59060.1 | SAMN02746011_00479 | SAMN02746011_01241 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA repair exonuclease SbcCD nuclease subunit. | 0.934 |
SJZ35590.1 | SJZ73013.1 | SAMN02746011_00479 | SAMN02746011_01620 | Exonuclease, DNA polymerase III, epsilon subunit family. | Superfamily I DNA and RNA helicases. | 0.780 |
SJZ35590.1 | SJZ77470.1 | SAMN02746011_00479 | SAMN02746011_01724 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.822 |
SJZ35590.1 | polA | SAMN02746011_00479 | SAMN02746011_01668 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.992 |
SJZ35590.1 | recA | SAMN02746011_00479 | SAMN02746011_00435 | Exonuclease, DNA polymerase III, epsilon subunit family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.682 |
SJZ35590.1 | recD2 | SAMN02746011_00479 | SAMN02746011_00554 | Exonuclease, DNA polymerase III, epsilon subunit family. | Exodeoxyribonuclease V alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.554 |
SJZ35590.1 | topA | SAMN02746011_00479 | SAMN02746011_00785 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.893 |
SJZ35590.1 | truB | SAMN02746011_00479 | SAMN02746011_00796 | Exonuclease, DNA polymerase III, epsilon subunit family. | tRNA pseudouridine55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.668 |
SJZ59060.1 | SJZ35590.1 | SAMN02746011_01241 | SAMN02746011_00479 | DNA repair exonuclease SbcCD nuclease subunit. | Exonuclease, DNA polymerase III, epsilon subunit family. | 0.934 |
SJZ59060.1 | SJZ73013.1 | SAMN02746011_01241 | SAMN02746011_01620 | DNA repair exonuclease SbcCD nuclease subunit. | Superfamily I DNA and RNA helicases. | 0.586 |
SJZ59060.1 | SJZ77470.1 | SAMN02746011_01241 | SAMN02746011_01724 | DNA repair exonuclease SbcCD nuclease subunit. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.586 |
SJZ59060.1 | addA | SAMN02746011_01241 | SAMN02746011_01171 | DNA repair exonuclease SbcCD nuclease subunit. | DNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase. | 0.450 |