STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepTPeptidase T. Metallo peptidase. MEROPS family M20B; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (411 aa)    
Predicted Functional Partners:
SJZ58645.1
Dinuclear metal center protein, YbgI/SA1388 family.
  
    0.836
SJZ58673.1
tRNA (adenine22-N1)-methyltransferase.
  
    0.773
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.581
SJZ40532.1
Xaa-Pro dipeptidase; Belongs to the peptidase M24B family.
  
 
 0.570
SJZ54180.1
Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family.
  
 
 0.570
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.556
SJZ84855.1
Cystathionine gamma-synthase.
    
 0.551
ddl
D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
 
 0.488
SJZ83906.1
Peptidase V. Metallo peptidase. MEROPS family M20A.
    
 0.477
SJZ36890.1
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 
 0.474
Your Current Organism:
Globicatella sulfidifaciens
NCBI taxonomy Id: 1121925
Other names: G. sulfidifaciens DSM 15739, Globicatella sulfidifaciens DSM 15739
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