node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ31959.1 | SJZ35590.1 | SAMN02746011_00244 | SAMN02746011_00479 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease, DNA polymerase III, epsilon subunit family. | 0.956 |
SJZ31959.1 | SJZ56226.1 | SAMN02746011_00244 | SAMN02746011_01155 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase-3 subunit epsilon. | 0.978 |
SJZ31959.1 | SJZ77470.1 | SAMN02746011_00244 | SAMN02746011_01724 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.855 |
SJZ31959.1 | ligA | SAMN02746011_00244 | SAMN02746011_01723 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.569 |
SJZ31959.1 | mutL | SAMN02746011_00244 | SAMN02746011_00572 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.975 |
SJZ31959.1 | recA | SAMN02746011_00244 | SAMN02746011_00435 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.869 |
SJZ35590.1 | SJZ31959.1 | SAMN02746011_00479 | SAMN02746011_00244 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.956 |
SJZ35590.1 | SJZ56226.1 | SAMN02746011_00479 | SAMN02746011_01155 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA polymerase-3 subunit epsilon. | 0.971 |
SJZ35590.1 | SJZ77470.1 | SAMN02746011_00479 | SAMN02746011_01724 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.822 |
SJZ35590.1 | ligA | SAMN02746011_00479 | SAMN02746011_01723 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.486 |
SJZ35590.1 | mutL | SAMN02746011_00479 | SAMN02746011_00572 | Exonuclease, DNA polymerase III, epsilon subunit family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.869 |
SJZ35590.1 | recA | SAMN02746011_00479 | SAMN02746011_00435 | Exonuclease, DNA polymerase III, epsilon subunit family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.682 |
SJZ56226.1 | SJZ31959.1 | SAMN02746011_01155 | SAMN02746011_00244 | DNA polymerase-3 subunit epsilon. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.978 |
SJZ56226.1 | SJZ35590.1 | SAMN02746011_01155 | SAMN02746011_00479 | DNA polymerase-3 subunit epsilon. | Exonuclease, DNA polymerase III, epsilon subunit family. | 0.971 |
SJZ56226.1 | SJZ77430.1 | SAMN02746011_01155 | SAMN02746011_01722 | DNA polymerase-3 subunit epsilon. | Protein involved in sex pheromone biosynthesis. | 0.511 |
SJZ56226.1 | SJZ77470.1 | SAMN02746011_01155 | SAMN02746011_01724 | DNA polymerase-3 subunit epsilon. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.857 |
SJZ56226.1 | gatA | SAMN02746011_01155 | SAMN02746011_01720 | DNA polymerase-3 subunit epsilon. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.464 |
SJZ56226.1 | gatC | SAMN02746011_01155 | SAMN02746011_01721 | DNA polymerase-3 subunit epsilon. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.414 |
SJZ56226.1 | mutL | SAMN02746011_01155 | SAMN02746011_00572 | DNA polymerase-3 subunit epsilon. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.427 |
SJZ56226.1 | recA | SAMN02746011_01155 | SAMN02746011_00435 | DNA polymerase-3 subunit epsilon. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.518 |