STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK19399.1Stage II sporulation protein E. (468 aa)    
Predicted Functional Partners:
SHJ35172.1
Sporulation factor SpoIIGA.
  
  
 0.956
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.903
SHJ23351.1
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.891
SHJ24545.1
Stage II sporulation protein P.
  
   
 0.884
SHJ95217.1
Anti-anti-sigma regulatory factor, SpoIIAA; Belongs to the anti-sigma-factor antagonist family.
  
  
 0.882
SHK19488.1
Sporulation protein YabP.
 
     0.877
SHJ34997.1
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.853
SHJ24038.1
Stage III sporulation protein AA.
  
   
 0.836
SHJ34672.1
Transcriptional regulator, AbrB family.
 
   
 0.834
SHK84712.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D.
  
   
 0.833
Your Current Organism:
Hespellia stercorisuis
NCBI taxonomy Id: 1121950
Other names: H. stercorisuis DSM 15480, Hespellia stercorisuis DSM 15480
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